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La Roche stops producing the Roaccutan, the most potent drug for acne and acne

Il farmaco più potente contro l'acne, il Roaccutan, non sarà più prodotto.La Roche, casa produttrice che lo commercializza negli Stati Uniti con il nome Accutane, ha deciso di sospendere la vendita, qui c'è la notizia in inglese . L'azienda lo ha comunicato alla stampa lo scorso venerdì 26 giugno 2009 sottolineando che si tratta di una scelta commerciale e non per ragioni di sicurezza legati agli effetti collaterali. Le vendite del farmaco hanno continuato a scendere affected by competition from the "generic" appeared on the market since 2002. Roaccutane, whose active ingredient is the 'isotretinoin, has for years been the reference point for those who had to fight very heavy forms of acne.
Born in 1971, is marketed in the United States in 1982 and 1983 lands in Europe. That same year, Public Citizen, an association of defense of U.S. consumers, asks the FDA (Federal Drug Administration) that are highlighted in 'anti-acne drug label warnings about the risk of birth defects in the presence of other side effects. Over the following years, Roche, driven by the FDA adds warnings of the drug on the other side effects: Some patients in the period following the therapy showed Roaccutan depression, psychosis and, rarely, suicide attempts and those who have experienced depression suicidio.Di some report that has fallen during the interruption of therapy and started again after taking the drug.
Roche defends that there is no evidence of causation and that adolescents are particularly at risk for depression. Roaccutan has as indicating severe cystic acne resistant to other therapies, in short, should be used for difficult cases to deal with any other type of therapy but dermatologists in the world tend to give even those with a 'light to medium acne. Another warning on the package is to avoid having be prescribed to women who are pregnant or may become pregnant, there would be no risk of malformations in the fetus. In essence, a powerful drug Roaccutane and acne. The undersigned has tried in 1988 and to tell the truth must emphasize that the treatment was effective for severe cystic acne. On this occasion, however, served as a shelter for even one week in hospital, I do not know whether to monitor the effects nDo you want or a form of precaution, however, the problem was resolved leaving scars in the face and slight in 'soul.

Some information in this article have been extrapolated from the site Actiongroup Roaccutan

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Pregnancy, pregnant worse?

Se c'è una tendenza individuale, in gravidanza l'acne può peggiorare. La gravidanza rappresenta uno sconvolgimento ormonale e fisico e durante questo periodo la quantità di sangue che affluisce alla pelle è quasi sestuplicata. L'aumento del flusso è determinato dalla dilatazione delle arteriole e dei capillari, i minuscoli vasi sanguigni che mettono in comunicazione le arterie e le vene, che è poi il meccanismo di cui il corpo si serve per mantenere stabile la temperatura esterna. A volte la pelle del viso, del tronco, delle braccia e del palmo delle mani può presentare macchie rossastre a causa del maggiore afflusso di sangue attraverso i vasi dilatati.L'acne a questo punto se già avevate una predisposizione potrebbe and worse if you use the antibiotic therapy should be discontinued if above all based on tetracycline.
After cleaning the face trying to keep it clean and rinse thoroughly with warm water to remove any residual sapone.Evitare to touch your pimples is the cause of spreading bacteria to other spots. Do not crush,
worsen your acne and contribute to scar formation. Always ask your doctor before resorting to drugs for acne, some are incompatible for pregnant women, such as Roaccutan.Comunque if acne is worse during pregnancy and in a particular way in the first three months of gestation usually disappears early.

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Acne brufoli, comedoni e punti neri, cosa sono e come si formano

What is acne and how it manifests, we see in detail what they mean pimples, blackheads and blacks.

Pimples: are small growths of skin color red, sometimes surmounted by a small white-yellowish, on the face and chest. Usually last a few days although they tend to recur and may result in unsightly scar. The pimple is not transmitted from one point to 'another of his skin and even to other people.

Black Point and Blackhead: across our skin, but especially numerous on the face and chest, there are many small sebaceous glands, ie, microscopic fabbriche deputate a produrre il grasso che espulso sulla pelle, serve a formare un sottile strato protettivo su di essa. Il comedone aperto è un piccolo tappo sulla ghiandola sebacea formato da cellule morte, batteri e polvere che impedisce la fuoriuscita dalla ghiandola delle sostanze grasse, che, trattenute, infiammano la pelle intorno alla ghiandola formando la papula rossa e la pustola giallastra e da qui si sviluppa l'acne. Tutto ciò è molto più accentuato guando il comedone è praticamente chiuso poiché in superficie c'è solo un piccolissimo foro e appare allora come una piccola cisti rilevata biancastra. In alcune persone invece c'è un difetto delle ghiandole sebacee per cui queste producono un eccesso di grasso che non riescono to expel the surface. The sebaceous ghiandoletta thickens and becomes inflamed, even to the presence of a bacterium that normally lives at the mouth of the gland (Corynebactenum acnes). Thus forming the pimple red and yellowish scab.

As the pustules form: sse and represent the latest step in the process of 'acne and are formed by the proliferation of certain bacteria in a sebaceous gland previously blocked by the black dot and filled with fat.

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L' Acne e ansia, quanto conta la psiche e lo stress

The relationship between acne and psyche have been widely diffused in the literature, if only for the obvious somatopsychic components of this disease, this which is moreover known to every dermatologist.
were studied some answers to a test by some people suffering from acne and some patients with "normal", the results showed that this condition is largely influenced by the psyche. I suffer from acne often demonstrate a lack of ego strength, revealing insecure and submissive, they are very tolerant to the frustrations of the environment. They are worried they are not sufficiently integrated into the group. There is often considerable emotional inhibition. Their super-ego (conscience) is pretty hard. Are conventional, and struggle to make a decision. Are tense and restless. Ergic tension is greatest, and this reveals the anxiety that moves from impulses of the id, in the face of a weak ego that is not always able to control impulses.
It should be remembered that in many subjects there is the presence of an authoritarian mother ("phallic mother") and that this experience is confirmed by the test. It has a clear predominance of hyperemotional-anxious subjects, a trend in many subjects, introversion, passivity, with a poor life for human contact. There is also lack of differentiation and structural stability of the ego, lack of adaptation to reality, shyness, significant inhibition. Often these patients reveal affectivity constricted, weak, poorly controlled, a formal social adaptation to normal levels, but only outwardly, a cau­sa di chiari fenomeni di inibizione.
L'esame del cospicuo materiale raccolto, in particolare quello de­gli acneici in cui la malattia è comparsa per la prima volta molti anni dopo l'adolescenza, induce a ritenere che la manifestazione dell' acne sia una patologia atta ad alleviare l'ansia. Papule e pustole creano in qualche modo un alibi somatico al paziente, il quale ridu­ce le occasioni, per lui molto ansiogene, di incontro con gli altri.
La drammatica scomparsa delle lesioni acneiche, ottenuta median­te terapia con isotretinoina, può indurre grosse difficoltà di adatta­mento alla nuova situazione, come si è rilevato in qualche caso. La nuova situazione di «non acne» tende a far abbandonare attending the dermatologist. The cases investigated are due to the presence of scars, which stay tends to perpetuate the 'advantages' psychological acne, and his suffering somatopsychic.